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Spatial positioning of CFTR’s pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway

The structural composition of CFTR’s anion permeation pathway has been proposed to consist of a short narrow region, flanked by two wide inner and outer vestibules, based on systematic cysteine scanning studies using thiol-reactive probes of various sizes. Although these studies identified several o...

詳細記述

保存先:
書誌詳細
出版年:J Gen Physiol
主要な著者: Gao, Xiaolong, Hwang, Tzyh-Chang
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845689/
https://ncbi.nlm.nih.gov/pubmed/27114613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511557
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