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Targeting translesion synthesis to facilitate the eradication of ovarian cancer stem cells by platinum-based therapy

Understanding the mechanisms by which cancer stem cells (CSCs) survive chemotherapy is essential for the development of new therapies. Recently, we demonstrated that ovarian CSCs survive cisplatin treatment through enhanced expression of DNA polymerase η (Pol η). Identification of micro RNA-93 (miR-...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Principais autores: Srivastava, Amit Kumar, Wang, Qi-En
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845331/
https://ncbi.nlm.nih.gov/pubmed/27308560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1043482
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