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Targeting translesion synthesis to facilitate the eradication of ovarian cancer stem cells by platinum-based therapy

Understanding the mechanisms by which cancer stem cells (CSCs) survive chemotherapy is essential for the development of new therapies. Recently, we demonstrated that ovarian CSCs survive cisplatin treatment through enhanced expression of DNA polymerase η (Pol η). Identification of micro RNA-93 (miR-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Oncol
Prif Awduron: Srivastava, Amit Kumar, Wang, Qi-En
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845331/
https://ncbi.nlm.nih.gov/pubmed/27308560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1043482
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