Development of EGFR Targeted Nanoemulsion for Imaging and Novel Platinum Therapy of Ovarian Cancer

PURPOSE: Platinum-based chemotherapy is the treatment of choice for malignant epithelial ovarian cancers, but generalized toxicity and platinum resistance limits its use. Theranostic nanoemulsion with a novel platinum prodrug, myrisplatin, and the pro-apoptotic agent, C(6)-ceramide, were designed to...

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Main Authors: Ganta, Srinivas, Singh, Amit, Patel, Niravkumar R., Cacaccio, Joseph, Rawal, Yashesh H., Davis, Barbara J., Amiji, Mansoor M., Coleman, Timothy P.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169355/
https://ncbi.nlm.nih.gov/pubmed/24643932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1345-z
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