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Targeting translesion synthesis to facilitate the eradication of ovarian cancer stem cells by platinum-based therapy

Understanding the mechanisms by which cancer stem cells (CSCs) survive chemotherapy is essential for the development of new therapies. Recently, we demonstrated that ovarian CSCs survive cisplatin treatment through enhanced expression of DNA polymerase η (Pol η). Identification of micro RNA-93 (miR-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Srivastava, Amit Kumar, Wang, Qi-En
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845331/
https://ncbi.nlm.nih.gov/pubmed/27308560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1043482
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