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Targeting translesion synthesis to facilitate the eradication of ovarian cancer stem cells by platinum-based therapy

Understanding the mechanisms by which cancer stem cells (CSCs) survive chemotherapy is essential for the development of new therapies. Recently, we demonstrated that ovarian CSCs survive cisplatin treatment through enhanced expression of DNA polymerase η (Pol η). Identification of micro RNA-93 (miR-...

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Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Main Authors: Srivastava, Amit Kumar, Wang, Qi-En
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845331/
https://ncbi.nlm.nih.gov/pubmed/27308560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1043482
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