A carregar...
Sustaining the spindle assembly checkpoint to improve cancer therapy
To prevent chromosome segregation errors, the spindle assembly checkpoint (SAC) delays mitosis exit until proper spindle assembly. We found that the FCP1 phosphatase and its downstream target WEE1 kinase oppose the SAC, promoting mitosis exit despite malformed spindles. We further showed that target...
Na minha lista:
| Publicado no: | Mol Cell Oncol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845201/ https://ncbi.nlm.nih.gov/pubmed/27308561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1046583 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|