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Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword
Major currently used anticancer therapeutics either directly damage DNA or target and upset basic cell division mechanisms like DNA replication and chromosome segregation. These insults elicit activation of cell cycle checkpoints, safeguard mechanisms that cells implement to correctly complete cell...
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| Gepubliceerd in: | J Exp Clin Cancer Res |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037895/ https://ncbi.nlm.nih.gov/pubmed/27670139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0433-9 |
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