Chronic hepatitis C viral infection subverts vaccine‐induced T‐cell immunity in humans

Adenoviral vectors encoding hepatitis C virus (HCV) nonstructural (NS) proteins induce multispecific, high‐magnitude, durable CD4(+) and CD8(+) T‐cell responses in healthy volunteers. We assessed the capacity of these vaccines to induce functional HCV‐specific immune responses and determine T‐cell c...

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發表在:Hepatology
Main Authors: Kelly, Christabel, Swadling, Leo, Capone, Stefania, Brown, Anthony, Richardson, Rachel, Halliday, John, von Delft, Annette, Oo, Ye, Mutimer, David, Kurioka, Ayako, Hartnell, Felicity, Collier, Jane, Ammendola, Virginia, Sorbo, Mariarosaria Del, Grazioli, Fabiana, Esposito, Maria Luisa, Marco, Stefania Di, Siani, Loredana, Traboni, Cinzia, Hill, Adrian V.S., Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Folgori, Antonella, Klenerman, Paul, Barnes, Eleanor
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Viral Hepatitis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842008/
https://ncbi.nlm.nih.gov/pubmed/26474390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28294
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