Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man

Currently no vaccine exists for hepatitis C virus (HCV), a major pathogen thought to infect 170 million people globally. Many studies suggest that host T cell responses are critical for spontaneous resolution of disease, and preclinical studies have indicated a requirement for T cells in protection...

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Detalhes bibliográficos
Main Authors: Barnes, Eleanor, Folgori, Antonella, Capone, Stefania, Swadling, Leo, Aston, Stephen, Kurioka, Ayako, Meyer, Joel, Huddart, Rachel, Smith, Kira, Townsend, Rachel, Brown, Anthony, Antrobus, Richard, Ammendola, Virginia, Naddeo, Mariarosaria, O’Hara, Geraldine, Willberg, Chris, Harrison, Abby, Grazioli, Fabiana, Esposito, Maria Luisa, Siani, Loredana, Traboni, Cinzia, Oo, Ye, Adams, David, Hill, Adrian, Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627207/
https://ncbi.nlm.nih.gov/pubmed/22218690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003155
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