A Human Vaccine Strategy Based On Chimpanzee Adenoviral and MVA Vectors That Primes, Boosts and Sustains Functional HCV Specific T-Cell Memory

A protective vaccine against hepatitis C virus (HCV) remains an unmet clinical need. HCV infects millions of people worldwide and is a leading cause of liver cirrhosis and hepatocellular cancer. Animal challenge experiments, immunogenetics studies and assessment of host immunity during acute infecti...

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Bibliografski detalji
Izdano u:Sci Transl Med
Glavni autori: Swadling, Leo, Capone, Stefania, Antrobus, Richard D., Brown, Anthony, Richardson, Rachel, Newell, Evan W., Halliday, John, Kelly, Christabel, Bowen, Dan, Fergusson, Joannah, Kurioka, Ayako, Ammendola, Virginia, Sorbo, Mariarosaria Del, Grazioli, Fabiana, Esposito, Maria Luisa, Siani, Loredana, Traboni, Cinzia, Hill, Adrian, Colloca, Stefano, Davis, Mark, Nicosia, Alfredo, Cortese, Riccardo, Folgori, Antonella, Klenerman, Paul, Barnes, Eleanor
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669853/
https://ncbi.nlm.nih.gov/pubmed/25378645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009185
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