Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection

An effective therapeutic vaccine for the treatment of chronic hepatitis C virus (HCV) infection, as an adjunct to newly developed directly-acting antivirals (DAA), or for the prevention of reinfection, would significantly reduce the global burden of disease associated with chronic HCV infection. A r...

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Udgivet i:Vaccines (Basel)
Main Authors: Swadling, Leo, Halliday, John, Kelly, Christabel, Brown, Anthony, Capone, Stefania, Ansari, M. Azim, Bonsall, David, Richardson, Rachel, Hartnell, Felicity, Collier, Jane, Ammendola, Virginia, Del Sorbo, Mariarosaria, Von Delft, Annette, Traboni, Cinzia, Hill, Adrian V. S., Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Klenerman, Paul, Folgori, Antonella, Barnes, Eleanor
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041021/
https://ncbi.nlm.nih.gov/pubmed/27490575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines4030027
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