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Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells

DNA double-strand breaks (DSBs) are repaired by either homologous recombination (HR) or non-homologous end joining (NHEJ) in mammalian cells. Repair with NHEJ or HR using single-strand annealing (SSA) often results in deletions and is generally referred to as non-conservative recombination. Error-fr...

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Autori principali: Saleh-Gohari, Nasrollah, Helleday, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC484186/
https://ncbi.nlm.nih.gov/pubmed/15252152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh703
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