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The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle

DNA double-strand breaks (DSBs) are dangerous lesions that can lead to genomic instability and cell death. Eukaryotic cells repair DSBs either by nonhomologous end-joining (NHEJ) or by homologous recombination. We investigated the ability of yeast cells (Saccharomyces cerevisiae) to repair a single,...

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Detalhes bibliográficos
Main Authors: Aylon, Yael, Liefshitz, Batia, Kupiec, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535085/
https://ncbi.nlm.nih.gov/pubmed/15549137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600469
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