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(99m)Tc-bioorthogonal click chemistry reagent for in vivo pretargeted imaging
Metal-free click chemistry has become an important tool for pretargeted approaches in the molecular imaging field. The application of bioorthogonal click chemistry between a pretargeted trans-cyclooctene (TCO) derivatized monoclonal antibody (mAb) and a (99m)Tc-modified 1,2,4,5-tetrazine for tumor i...
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| Publié dans: | Bioorg Med Chem |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4841469/ https://ncbi.nlm.nih.gov/pubmed/26875936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.01.046 |
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