Synthetic Medicinal Chemistry in Chagas’ Disease: Compounds at The Final Stage of “Hit-To-Lead” Phase

por Cerecetto, Hugo, González, Mercedes
Publicado 2010

Cathepsin L Inhibitors with Activity against the Liver Fluke Identified From a Focus Library of Quinoxaline 1,4-di-N-Oxide Derivatives

por Ferraro, Florencia, Merlino, Alicia, Gil, Jorge, Cerecetto, Hugo, Corvo, Ileana, Cabrera, Mauricio
Publicado en Molecules (2019)

Development, Characterization, and In Vitro Biological Performance of Fluconazole-Loaded Microemulsions for the Topical Treatment of Cutaneous Leishmaniasis

por Oliveira, Marcela Brito, Calixto, Giovana, Graminha, Márcia, Cerecetto, Hugo, González, Mercedes, Chorilli, Marlus
Publicado en Biomed Res Int (2015)

Evaluating 5-Nitrofurans as Trypanocidal Agents

por Bot, Christopher, Hall, Belinda S., Álvarez, Guzmán, Di Maio, Rossanna, González, Mercedes, Cerecetto, Hugo, Wilkinson, Shane R.
Publicado 2013

(99m)Tc-bioorthogonal click chemistry reagent for in vivo pretargeted imaging

por García, María Fernanda, Zhang, Xiuli, Shah, Manankumar, Newton-Northup, Jessica, Cabral, Pablo, Cerecetto, Hugo, Quinn, Thomas
Publicado en Bioorg Med Chem (2016)

In vitro and in vivo uptake studies of PAMAM G4.5 dendrimers in breast cancer

por Oddone, Natalia, Lecot, Nicole, Fernández, Marcelo, Rodriguez-Haralambides, Alejandra, Cabral, Pablo, Cerecetto, Hugo, Benech, Juan Claudio
Publicado en J Nanobiotechnology (2016)

Identification of N-Oxide-Containing Aromatic Heterocycles as Pharmacophores for Rumen Fermentation Modifiers

por Bonifacino, Carla, Rodríguez, Gonzalo, Pérez-Ruchel, Analía, Repetto, José Luis, Cerecetto, Hugo, Cajarville, Cecilia, González, Mercedes
Publicado en Metabolites (2019)

Identification of Chalcones as Fasciola hepatica Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach

por Ferraro, Florencia, Merlino, Alicia, dell´Oca, Nicolás, Gil, Jorge, Tort, José F., Gonzalez, Mercedes, Cerecetto, Hugo, Cabrera, Mauricio, Corvo, Ileana
Publicado en PLoS Negl Trop Dis (2016)

Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment

por Aguilera, Elena, Varela, Javier, Serna, Elva, Torres, Susana, Yaluff, Gloria, de Bilbao, Ninfa Vera, Cerecetto, Hugo, Alvarez, Guzmán, González, Mercedes
Publicado en Mem Inst Oswaldo Cruz (2018)

In Vivo Anti-Trypanosoma cruzi Activity of Hydro-Ethanolic Extract and Isolated Active Principles from Aristeguietia glutinosa and Mechanism of Action Studies

por Varela, Javier, Serna, Elva, Torres, Susana, Yaluff, Gloria, de Bilbao, Ninfa I. Vera, Miño, Patricio, Chiriboga, Ximena, Cerecetto, Hugo, González, Mercedes
Publicado en Molecules (2014)

Formation of dendrimer-guest complexes as a strategy to increase the solubility of a phenazine N, N′-dioxide derivative with antitumor activity

por Dib, Nahir, Fernández, Luciana, Santo, Marisa, Otero, Luis, Alustiza, Fabrisio, Liaudat, Ana Cecilia, Bosch, Pablo, Lavaggi, M. Laura, Cerecetto, Hugo, González, Mercedes
Publicado en Heliyon (2019)

New hits as phase II enzymes inducers from a focused library with heteroatom–heteroatom and Michael-acceptor motives

por Cabrera, Mauricio, de Ovalle, Stefani, Bollati-Fogolín, Mariela, Nascimento, Fabiana, Corbelini, Patrícia, Janarelli, Fernanda, Kawano, Daniel, Eifler-Lima, Vera Lucia, González, Mercedes, Cerecetto, Hugo
Publicado en Future Sci OA (2015)

Relationship Between Physicochemical Properties and Herbicidal Activity of 1,2,5-Oxadiazole N-Oxide Derivatives

por Fernandez, Luciana A., Santo, Marisa R., Reta, Mario, Giacomelli, Liliana, Cattana, Rosa, Silber, Juana J., Risso, Mariela, Cerecetto, Hugo, Gonzalez, Mercedes, Olea-Azar, Claudio
Publicado en Molecules (2005)

Risedronate metal complexes potentially active against Chagas disease

por Demoro, Bruno, Caruso, Francesco, Rossi, Miriam, Benítez, Diego, Gonzalez, Mercedes, Cerecetto, Hugo, Parajón-Costa, Beatriz, Castiglioni, Jorge, Galizzi, Melina, Docampo, Roberto, Otero, Lucía, Gambino, Dinorah
Publicado 2010

Heterocyclic-2-carboxylic Acid (3-Cyano-1,4-di-N-oxidequinoxalin-2-yl)amide Derivatives as Hits for the Development of Neglected Disease Drugs

por Ancizu, Saioa, Moreno, Elsa, Torres, Enrique, Burguete, Asunción, Pérez-Silanes, Silvia, Benítez, Diego, Villar, Raquel, Solano, Beatriz, Marín, Adoración, Aldana, Ignacio, Cerecetto, Hugo, González, Mercedes, Monge, Antonio
Publicado en Molecules (2009)

Closo-Carboranyl- and Metallacarboranyl [1,2,3]triazolyl-Decorated Lapatinib-Scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy

por Couto, Marcos, Alamón, Catalina, García, María Fernanda, Kovacs, Mariángeles, Trias, Emiliano, Nievas, Susana, Pozzi, Emiliano, Curotto, Paula, Thorp, Silvia, Dagrosa, María Alejandra, Teixidor, Francesc, Viñas, Clara, Cerecetto, Hugo
Publicado en Cells (2020)

Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity

por Alamón, Catalina, Dávila, Belén, García, María Fernanda, Sánchez, Carina, Kovacs, Mariángeles, Trias, Emiliano, Barbeito, Luis, Gabay, Martín, Zeineh, Nidal, Gavish, Moshe, Teixidor, Francesc, Viñas, Clara, Couto, Marcos, Cerecetto, Hugo
Publicado en Cancers (Basel) (2020)

Identification of Thioredoxin Glutathione Reductase Inhibitors That Kill Cestode and Trematode Parasites

por Ross, Fabiana, Hernández, Paola, Porcal, Williams, López, Gloria V., Cerecetto, Hugo, González, Mercedes, Basika, Tatiana, Carmona, Carlos, Fló, Martín, Maggioli, Gabriela, Bonilla, Mariana, Gladyshev, Vadim N., Boiani, Mariana, Salinas, Gustavo
Publicado 2012

Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp.

por Álvarez, Guzmán, Perdomo, Cintya, Coronel, Cathia, Aguilera, Elena, Varela, Javier, Aparicio, Gonzalo, Zolessi, Flavio R., Cabrera, Nallely, Vega, Celeste, Rolón, Miriam, Rojas de Arias, Antonieta, Pérez-Montfort, Ruy, Cerecetto, Hugo, González, Mercedes
Publicado en Molecules (2017)

Estudos de otimização do protótipo antiinflamatório e analgésico LASSBIO-259 /

por Faoro, Débora, Barreiro, Eliezer Jesus, Fraga, Carlos Alberto Manssour, Cerecetto, Hugo, Zanatta, Nilo, Ferreira, Vitor Francisco, Lima, Lídia Moreira, Pinto, Ângelo da Cunha, Kaiser, Carlos Roland, Universidade Federal do Rio de Janeiro.
Publicado 2006.