New hits as phase II enzymes inducers from a focused library with heteroatom–heteroatom and Michael-acceptor motives

The increased activity of phase-II-detoxification enzymes, such as quinone reductase (QR) and glutation S-transferase (GST), correlates with protection against chemically induced carcinogenesis. Herein we studied 11 different chemotypes, pyrazole, 1,2,4-oxadiazole, 1,2,5-oxadiazole, 1,2,3-thiadiazol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Future Sci OA
Main Authors: Cabrera, Mauricio, de Ovalle, Stefani, Bollati-Fogolín, Mariela, Nascimento, Fabiana, Corbelini, Patrícia, Janarelli, Fernanda, Kawano, Daniel, Eifler-Lima, Vera Lucia, González, Mercedes, Cerecetto, Hugo
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137958/
https://ncbi.nlm.nih.gov/pubmed/28031894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fso.15.18
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados