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Evaluating 5-Nitrofurans as Trypanocidal Agents
The nitroheterocycle nifurtimox, as part of a nifurtimox-eflornithine combination therapy, represents one of a limited number of treatments targeting Trypanosoma brucei, the causative agent of human African trypanosomiasis. The mode of action of this prodrug involves an initial activation reaction c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623332/ https://ncbi.nlm.nih.gov/pubmed/23335745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02046-12 |
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