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Cathepsin L Inhibitors with Activity against the Liver Fluke Identified From a Focus Library of Quinoxaline 1,4-di-N-Oxide Derivatives

Infections caused by Fasciola species are widely distributed in cattle and sheep causing significant economic losses, and are emerging as human zoonosis with increasing reports of human cases, especially in children in endemic areas. The current treatment is chemotherapeutic, triclabendazole being t...

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Библиографические подробности
Опубликовано в: :Molecules
Главные авторы: Ferraro, Florencia, Merlino, Alicia, Gil, Jorge, Cerecetto, Hugo, Corvo, Ileana, Cabrera, Mauricio
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651555/
https://ncbi.nlm.nih.gov/pubmed/31247891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24132348
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