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Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment
BACKGROUND: The current chemotherapy for Chagas disease is based on monopharmacology with low efficacy and drug tolerance. Polypharmacology is one of the strategies to overcome these limitations. OBJECTIVES: Study the anti-Trypanosoma cruzi activity of associations of benznidazole (Bnz) with three n...
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| Publicat a: | Mem Inst Oswaldo Cruz |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Instituto Oswaldo Cruz, Ministério da Saúde
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5804306/ https://ncbi.nlm.nih.gov/pubmed/29412353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760170267 |
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