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Epithelial Junction Opener Improves Oncolytic Adenovirus Therapy in Mouse Tumor Models
A central resistance mechanism in solid tumors is the maintenance of epithelial junctions between malignant cells that prevent drug penetration into the tumor. Human adenoviruses (Ads) have evolved mechanisms to breach epithelial barriers. For example, during Ad serotype 3 (Ad3) infection of epithel...
Shranjeno v:
| izdano v: | Hum Gene Ther |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Mary Ann Liebert, Inc.
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4840918/ https://ncbi.nlm.nih.gov/pubmed/26993072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.022 |
| Oznake: |
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