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Multimerization of Adenovirus Serotype 3 Fiber Knob Domains Is Required for Efficient Binding of Virus to Desmoglein 2 and Subsequent Opening of Epithelial Junctions

Recently, we identified desmoglein 2 (DSG2) as the main receptor for a group of species B adenoviruses (Ads), including Ad3, a serotype that is widely distributed in the human population (H. Wang et al., Nat. Med. 17:96–104, 2011). In this study, we have attempted to delineate structural details of...

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Библиографические подробности
Главные авторы: Wang, Hongjie, Li, ZongYi, Yumul, Roma, Lara, Stephanie, Hemminki, Akseli, Fender, Pascal, Lieber, André
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112237/
https://ncbi.nlm.nih.gov/pubmed/21525338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00514-11
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