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Co-administration of epithelial junction opener JO-1 improves the efficacy and safety of chemotherapeutic drugs

PURPOSE: Epithelial junctions between tumor cells inhibit the penetration of anti-cancer drugs into tumors. We previously reported on recombinant adenovirus serotype 3 derived protein (JO-1), which triggers transient opening of intercellular junctions in epithelial tumors through binding to desmogle...

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Detalhes bibliográficos
Main Authors: Beyer, Ines, Cao, Hua, Persson, Jonas, Song, Hui, Richter, Maximilian, Feng, Qinghua, Yumul, Roma, van Rensburg, Ruan, Li, Zongyi, Berenson, Ronald, Carter, Darrick, Roffler, Steve, Drescher, Charles, Lieber, André
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547677/
https://ncbi.nlm.nih.gov/pubmed/22535153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3213
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