Immuno-Therapy with Anti-CTLA4 Antibodies in Tolerized and Non-Tolerized Mouse Tumor Models

Monoclonal antibodies specific for cytotoxic T lymphocyte-associated antigen 4 (anti-CTLA4) are a novel form of cancer immunotherapy. While preclinical studies in mouse tumor models have shown anti-tumor efficacy of anti-CTLA4 injection or expression, anti-CTLA4 treatment in patients with advanced c...

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Main Authors: Persson, Jonas, Beyer, Ines, Yumul, Roma, Li, ZongYi, Kiem, Hans-Peter, Roffler, Steve, Lieber, André
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136517/
https://ncbi.nlm.nih.gov/pubmed/21779410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022303
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