Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy

Defensins are small antimicrobial peptides capable of neutralizing human adenovirus (HAdV) in vitro by binding capsid proteins and blocking endosomal escape of virus. In humans, the alpha defensin HD5 is produced by specialized epithelial cells of the gastrointestinal and genito-urinary tracts. Here...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Vragniau, Charles, Hübner, Jens-Martin, Beidler, Peter, Gil, Sucheol, Saydaminova, Kamola, Lu, Zhuo-Zhuang, Yumul, Roma, Wang, Hongjie, Richter, Maximilian, Sova, Pavel, Drescher, Charles, Fender, Pascal, Lieber, André
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331826/
https://ncbi.nlm.nih.gov/pubmed/28077642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02030-16
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