Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy

Defensins are small antimicrobial peptides capable of neutralizing human adenovirus (HAdV) in vitro by binding capsid proteins and blocking endosomal escape of virus. In humans, the alpha defensin HD5 is produced by specialized epithelial cells of the gastrointestinal and genito-urinary tracts. Here...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Vragniau, Charles, Hübner, Jens-Martin, Beidler, Peter, Gil, Sucheol, Saydaminova, Kamola, Lu, Zhuo-Zhuang, Yumul, Roma, Wang, Hongjie, Richter, Maximilian, Sova, Pavel, Drescher, Charles, Fender, Pascal, Lieber, André
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331826/
https://ncbi.nlm.nih.gov/pubmed/28077642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02030-16
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