USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response

Dynamic regulation of RNF168-mediated ubiquitylation of histone H2A Lys13,15 (H2AK13,15ub) at DNA double-strand breaks (DSBs) is crucial for preventing aberrant DNA repair and maintaining genome stability. However, it remains unclear which deubiquitylating enzyme (DUB) removes H2AK13,15ub. Here we s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Wang, Zhiquan, Zhang, Honglian, Liu, Ji, Cheruiyot, Abigael, Lee, Jeong-Heon, Ordog, Tamas, Lou, Zhenkun, You, Zhongsheng, Zhang, Zhiguo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840300/
https://ncbi.nlm.nih.gov/pubmed/27083998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271841.115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados