Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes

BACKGROUND: The clinical utility of primaquine (PQ), used as a racemic mixture of two enantiomers, is limited due to metabolism-linked hemolytic toxicity in individuals with genetic deficiency in glucose-6-phosphate dehydrogenase. The current study investigated differential metabolism of PQ enantiom...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Malar J
Asıl Yazarlar: Fasinu, Pius S., Avula, Bharathi, Tekwani, Babu L., Nanayakkara, N. P. Dhammika, Wang, Yan-Hong, Bandara Herath, H. M. T., McChesney, James D., Reichard, Gregory A., Marcsisin, Sean R., Elsohly, Mahmoud A., Khan, Shabana I., Khan, Ikhlas A., Walker, Larry A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837544/
https://ncbi.nlm.nih.gov/pubmed/27093859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1270-1
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller