Onset of leptin resistance shows temporal differences related to dose or pulsed treatment

Leptin administration results in leptin resistance presenting a significant barrier to therapeutic use of leptin. Consequently, we examined two hypotheses. The first examined the relationship between leptin dose and development of physiological and biochemical signs of leptin resistance. We hypothes...

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Bibliographic Details
Published in:Eur J Pharmacol
Main Authors: Strehler, Kevin Y.E., Matheny, Michael, Kirichenko, Nataliya, Sakarya, Yasemin, Bruce, Erin, Toklu, Hale Zerrin, Carter, Christy S., Morgan, Drake, Tümer, Nihal, Scarpace, Philip J.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837473/
https://ncbi.nlm.nih.gov/pubmed/27012992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.03.026
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