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Anorexic response to rapamycin does not appear to involve a central mechanism
The authors have previously demonstrated that a low and intermittent peripheral dose of rapamycin (1 mg/kg three times/week) to rats inhibited mTORC1 signalling, but avoided the hyperlipidemia and diabetes-like syndrome associated with higher doses of rapamycin. The dosing regimen reduced food intak...
Kaydedildi:
| Yayımlandı: | Clin Exp Pharmacol Physiol |
|---|---|
| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522742/ https://ncbi.nlm.nih.gov/pubmed/27232670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12601 |
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