Onset of leptin resistance shows temporal differences related to dose or pulsed treatment

Leptin administration results in leptin resistance presenting a significant barrier to therapeutic use of leptin. Consequently, we examined two hypotheses. The first examined the relationship between leptin dose and development of physiological and biochemical signs of leptin resistance. We hypothes...

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Bibliografiske detaljer
Udgivet i:Eur J Pharmacol
Main Authors: Strehler, Kevin Y.E., Matheny, Michael, Kirichenko, Nataliya, Sakarya, Yasemin, Bruce, Erin, Toklu, Hale Zerrin, Carter, Christy S., Morgan, Drake, Tümer, Nihal, Scarpace, Philip J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837473/
https://ncbi.nlm.nih.gov/pubmed/27012992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.03.026
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