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Onset of leptin resistance shows temporal differences related to dose or pulsed treatment

Leptin administration results in leptin resistance presenting a significant barrier to therapeutic use of leptin. Consequently, we examined two hypotheses. The first examined the relationship between leptin dose and development of physiological and biochemical signs of leptin resistance. We hypothes...

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書誌詳細
出版年:Eur J Pharmacol
主要な著者: Strehler, Kevin Y.E., Matheny, Michael, Kirichenko, Nataliya, Sakarya, Yasemin, Bruce, Erin, Toklu, Hale Zerrin, Carter, Christy S., Morgan, Drake, Tümer, Nihal, Scarpace, Philip J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837473/
https://ncbi.nlm.nih.gov/pubmed/27012992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.03.026
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