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GSTZ1 Expression and Chloride Concentrations Modulate Sensitivity of Cancer Cells to Dichloroacetate
Dichloroacetate (DCA), commonly used to treat metabolic disorders, is under investigation as an anti-cancer therapy due to its ability to reverse the Warburg effect and induce apoptosis in tumor cells. While DCA’s mechanism of action is well-studied, other factors that influence its potential as a c...
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| 出版年: | Biochim Biophys Acta |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837035/ https://ncbi.nlm.nih.gov/pubmed/26850694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.01.024 |
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