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Chloride concentrations in human hepatic cytosol and mitochondria are a function of age

We recently reported that, in a concentration-dependent manner, chloride protects hepatic glutathione transferase zeta 1 from inactivation by dichloroacetate, an investigational drug used in treating various acquired and congenital metabolic diseases. Despite the importance of chloride ions in norma...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Jahn, Stephan C., Rowland-Faux, Laura, Stacpoole, Peter W., James, Margaret O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380591/
https://ncbi.nlm.nih.gov/pubmed/25748576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.128
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