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Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria

PURPOSE: To analyze the relationship between ARMS2 and HTRA1 in the association with age-related macular degeneration (AMD) in an independent case-control dataset, and to investigate the subcellular localization of the ARMS2 protein in an in vitro system. METHOD: Two SNPs in ARMS2 and HTRA1 were gen...

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Detalhes bibliográficos
Main Authors: Wang, Gaofeng, Spencer, Kylee L., Court, Brenda L., Olson, Lana M., Scott, William K., Haines, Jonathan L., Pericak-Vance, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001322/
https://ncbi.nlm.nih.gov/pubmed/19255159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-3240
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