Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes

Previous work has shown that hepatic levels of human glutathione transferase zeta 1 (GSTZ1) protein, involved in tyrosine catabolism and responsible for metabolism of the investigational drug dichloroacetate, increase in cytosol after birth before reaching a plateau around age 7. However, the mechan...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Drug Metab Dispos
Hoofdauteurs: Jahn, Stephan C., Gay, Lauren A., Weaver, Claire J., Renne, Rolf, Langaee, Taimour Y., Stacpoole, Peter W., James, Margaret O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2020
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289049/
https://ncbi.nlm.nih.gov/pubmed/32357971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.120.090639
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items