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Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes
Previous work has shown that hepatic levels of human glutathione transferase zeta 1 (GSTZ1) protein, involved in tyrosine catabolism and responsible for metabolism of the investigational drug dichloroacetate, increase in cytosol after birth before reaching a plateau around age 7. However, the mechan...
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| Vydáno v: | Drug Metab Dispos |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289049/ https://ncbi.nlm.nih.gov/pubmed/32357971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.120.090639 |
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