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Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes
Previous work has shown that hepatic levels of human glutathione transferase zeta 1 (GSTZ1) protein, involved in tyrosine catabolism and responsible for metabolism of the investigational drug dichloroacetate, increase in cytosol after birth before reaching a plateau around age 7. However, the mechan...
Tallennettuna:
| Julkaisussa: | Drug Metab Dispos |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289049/ https://ncbi.nlm.nih.gov/pubmed/32357971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.120.090639 |
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