A U1 snRNP-Specific Assembly Pathway Reveals the SMN Complex as a Versatile RNP Exchange

Despite their equal stoichiometry in spliceosomes, U1 snRNP (U1) is typically the most abundant snRNP in vertebrates. What regulates U1 over-abundance and snRNP repertoire in general is unknown. Sm core assembly is a key step in snRNP biogenesis mediated by the SMN complex. All pre-snRNAs are delive...

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Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: So, Byung Ran, Wan, Lili, Zhang, Zhenxi, Li, Pilong, Babiash, Eric, Duan, Jingqi, Younis, Ihab, Dreyfuss, Gideon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834709/
https://ncbi.nlm.nih.gov/pubmed/26828962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3167
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