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A U1 snRNP-Specific Assembly Pathway Reveals the SMN Complex as a Versatile RNP Exchange
Despite their equal stoichiometry in spliceosomes, U1 snRNP (U1) is typically the most abundant snRNP in vertebrates. What regulates U1 over-abundance and snRNP repertoire in general is unknown. Sm core assembly is a key step in snRNP biogenesis mediated by the SMN complex. All pre-snRNAs are delive...
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| הוצא לאור ב: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834709/ https://ncbi.nlm.nih.gov/pubmed/26828962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3167 |
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