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U1 snRNP telescripting regulates a size–function-stratified human genome
U1 snRNP (U1) functions in splicing introns and telescripting, which suppresses premature cleavage and polyadenylation (PCPA). Using U1 inhibition in human cells, we show that U1 telescripting is selectively required for sustaining long-distance transcription elongation in introns of large genes (me...
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| Publicat a: | Nat Struct Mol Biol |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685549/ https://ncbi.nlm.nih.gov/pubmed/28967884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3473 |
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