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U1 snRNP Determines mRNA Length and Regulates Isoform Expression
U1 snRNP (U1), in addition to its splicing role, protects pre-mRNAs from drastic premature termination by cleavage and polyadenylation (PCPA) at cryptic polyadenylation signals (PASs) in introns. Here, a high throughput sequencing strategy of differentially expressed transcripts (HIDE-seq), mapped P...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412174/ https://ncbi.nlm.nih.gov/pubmed/22770214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.029 |
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