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Structure Property Relationships of Carboxylic Acid Isosteres
[Image: see text] The replacement of a carboxylic acid with a surrogate structure, or (bio)-isostere, is a classical strategy in medicinal chemistry. The general underlying principle is that by maintaining the features of the carboxylic acid critical for biological activity, but appropriately modify...
Zapisane w:
| Wydane w: | J Med Chem |
|---|---|
| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2016
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833640/ https://ncbi.nlm.nih.gov/pubmed/26967507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01963 |
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