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Interaction with the Paxillin LD1 Motif Relieves MEKK2 Auto-inhibition
The cell signaling molecule MEK kinase 2 (MEKK2) is a key upstream regulator of MAPK activity that regulates numerous cellular functions, but the mechanisms that control MEKK2 activity are not well understood. Recently, we reported that MEKK2 both binds and promotes ubiquitylation of the scaffold pr...
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| 出版年: | J Mol Signal |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Ubiquity Press
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831274/ https://ncbi.nlm.nih.gov/pubmed/27096002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5334/1750-2187-10-4 |
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