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Interaction with the Paxillin LD1 Motif Relieves MEKK2 Auto-inhibition

The cell signaling molecule MEK kinase 2 (MEKK2) is a key upstream regulator of MAPK activity that regulates numerous cellular functions, but the mechanisms that control MEKK2 activity are not well understood. Recently, we reported that MEKK2 both binds and promotes ubiquitylation of the scaffold pr...

詳細記述

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書誌詳細
出版年:J Mol Signal
主要な著者: Kahle, Michael P., Cuevas, Bruce D.
フォーマット: Artigo
言語:Inglês
出版事項: Ubiquity Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831274/
https://ncbi.nlm.nih.gov/pubmed/27096002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5334/1750-2187-10-4
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