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GIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 Motifs

The G protein-coupled receptor kinase-interacting protein 1 (GIT1) is a multidomain protein that plays an important role in cell adhesion, motility, cytoskeletal remodeling, and membrane trafficking. GIT1 mediates the localization of the p21-activated kinase (PAK) and PAK-interactive exchange factor...

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Detalles Bibliográficos
Main Authors: Zhang, Ziwei M., Simmerman, Joseph A., Guibao, Cristina D., Zheng, Jie J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441563/
https://ncbi.nlm.nih.gov/pubmed/18448431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801274200
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