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Phosphorylation of Paxillin LD4 Destabilizes Helix Formation and Inhibits Binding to Focal Adhesion Kinase

Cell migration is a dynamic process that requires the coordinated formation and disassembly of focal adhesions (FAs). Several proteins such as paxillin, focal adhesion kinase (FAK), and G protein–coupled receptor kinase–interacting protein 1 (GIT1) are known to play a regulatory role in FA disassemb...

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Bibliographic Details
Main Authors: Bertolucci, Craig M., Guibao, Cristina D., Zheng, Jie J.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054611/
https://ncbi.nlm.nih.gov/pubmed/18092823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702103n
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