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Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin

The adaptor protein paxillin contains five conserved leucine-rich (LD) motifs that interact with a variety of focal adhesion proteins, such as α-parvin. Here, we report the first crystal structure of the C-terminal calponin homology domain (CH(C)) of α-parvin at 1.05 Å resolution and show that it is...

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Hlavní autoři: Lorenz, Sonja, Vakonakis, Ioannis, Lowe, Edward D., Campbell, Iain D., Noble, Martin E.M., Hoellerer, Maria K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572193/
https://ncbi.nlm.nih.gov/pubmed/18940607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.08.007
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