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The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL)

The small GTPases of the Rho family are intimately involved in integrin-mediated changes in the actin cytoskeleton that accompany cell spreading and motility. The exact means by which the Rho family members elicit these changes is unclear. Here, we demonstrate that the interaction of paxillin via it...

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Detalhes bibliográficos
Main Authors: West, Kip A., Zhang, Huaye, Brown, Michael C., Nikolopoulos, Sotiris N., Riedy, M.C., Horwitz, Alan F., Turner, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196859/
https://ncbi.nlm.nih.gov/pubmed/11448998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200101039
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