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MEKK2 Regulates Paxillin Ubiquitylation and Localization in MDA-MB 231 Breast Cancer Cells
The intracellular kinase MEK kinase 2 (MEKK2) is an upstream regulator of c-Jun amino-terminal kinase (JNK), but additional functions for MEKK2 have not been well defined. Silencing MEKK2 expression in invasive breast tumor cells markedly inhibits xenograft metastasis, indicating that MEKK2 controls...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467534/ https://ncbi.nlm.nih.gov/pubmed/25190348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140420 |
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