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MEKK2 Regulates Focal Adhesion Stability and Motility in Invasive Breast Cancer Cells
MEKK2 is a serine/threonine kinase that functions as a MAPKinase kinase kinase (MAP3K) to regulate activation of MAP kinases. We recently have demonstrated that ablation of MEKK2 expression in invasive breast tumor cells dramatically inhibits xenograft metastasis, but the mechanism by which MEKK2 in...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3960922/ https://ncbi.nlm.nih.gov/pubmed/24491810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.029 |
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