PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex

The invasive behavior of glioblastoma is essential to its aggressive potential. Here, we show that pleckstrin homology domain interacting protein (PHIP), acting through effects on the force transduction layer of the focal adhesion complex, drives glioblastoma motility and invasion. Immunofluorescenc...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Scanlon, Kara R., Singer, Eric, Judkins, Jonathon, Rieken, Christopher, Wu, Clayton, Shen, Julia, Schmudermayer, Christina, Dar, Altaf A., Miller, James R., Cobbs, Charles, Yount, Garret, Desprez, Pierre-Yves, Debs, Robert J., Salomonis, Nathan, McAllister, Sean, Cleaver, James E., Soroceanu, Liliana, Kashani-Sabet, Mohammed
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183218/
https://ncbi.nlm.nih.gov/pubmed/32273388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914505117
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi