PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex

The invasive behavior of glioblastoma is essential to its aggressive potential. Here, we show that pleckstrin homology domain interacting protein (PHIP), acting through effects on the force transduction layer of the focal adhesion complex, drives glioblastoma motility and invasion. Immunofluorescenc...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Scanlon, Kara R., Singer, Eric, Judkins, Jonathon, Rieken, Christopher, Wu, Clayton, Shen, Julia, Schmudermayer, Christina, Dar, Altaf A., Miller, James R., Cobbs, Charles, Yount, Garret, Desprez, Pierre-Yves, Debs, Robert J., Salomonis, Nathan, McAllister, Sean, Cleaver, James E., Soroceanu, Liliana, Kashani-Sabet, Mohammed
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183218/
https://ncbi.nlm.nih.gov/pubmed/32273388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914505117
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