PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer

The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Dar, Altaf A., Wu, Clayton, Shen, Julia, Rieken, Christopher, Venkatasubramanian, Meenakshi, Miller, James R., Desprez, Pierre-Yves, McAllister, Sean, Soroceanu, Liliana, Debs, Robert J., Salomonis, Nathan, Schadendorf, Dirk, Cleaver, James E., Kashani-Sabet, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016792/
https://ncbi.nlm.nih.gov/pubmed/29866840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804779115
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