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PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer

The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Dar, Altaf A., Wu, Clayton, Shen, Julia, Rieken, Christopher, Venkatasubramanian, Meenakshi, Miller, James R., Desprez, Pierre-Yves, McAllister, Sean, Soroceanu, Liliana, Debs, Robert J., Salomonis, Nathan, Schadendorf, Dirk, Cleaver, James E., Kashani-Sabet, Mohammed
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016792/
https://ncbi.nlm.nih.gov/pubmed/29866840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804779115
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