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PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer

The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Dar, Altaf A., Wu, Clayton, Shen, Julia, Rieken, Christopher, Venkatasubramanian, Meenakshi, Miller, James R., Desprez, Pierre-Yves, McAllister, Sean, Soroceanu, Liliana, Debs, Robert J., Salomonis, Nathan, Schadendorf, Dirk, Cleaver, James E., Kashani-Sabet, Mohammed
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016792/
https://ncbi.nlm.nih.gov/pubmed/29866840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804779115
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