PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer

The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: de Semir, David, Bezrookove, Vladimir, Nosrati, Mehdi, Dar, Altaf A., Wu, Clayton, Shen, Julia, Rieken, Christopher, Venkatasubramanian, Meenakshi, Miller, James R., Desprez, Pierre-Yves, McAllister, Sean, Soroceanu, Liliana, Debs, Robert J., Salomonis, Nathan, Schadendorf, Dirk, Cleaver, James E., Kashani-Sabet, Mohammed
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016792/
https://ncbi.nlm.nih.gov/pubmed/29866840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804779115
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